Agricultural Research Service - ARS

Dr. Duke's
Phytochemical and Ethnobotanical Databases

Chemicals and their Biological Activities in: Guazuma ulmifolia LAM. (Sterculiaceae) -- Bay Cedar


Chemicals

BETA-SITOSTEROL Plant: DUKE1992A
Androgenic DUKE1992B ; Anorexic MAR ; Antiadenomic M11 ; Antiandrogenic JE28:221 ; Antibacterial QJC28:155 ; Anticancer (Breast) PS131:95 ; Antiedemic IC54=320 mg/kg orl DFN:160 ; Antiestrogenic JE28:221 ; Antifeedant 382 ; Antifertility JE28:221 ; Antigonadotrophic JE28:221 ; Antihyperlipoproteinaemic JBH ; Antiinflammatory; Antileukemic PJB1(2):287 ; Antilymphomic PJB1(2):287 ; Antimutagenic 250 ug/mL JAFC37:1365 ; Antiophidic 2.3 mg mus EMP5:363 ; Antiprogestational JE28:221 ; Antiprostaglandin 30 mg/day/12 wks FT68(4):291 ; Antiprostatadenomic M11 ; Antiprostatitic 10-20 mg/3 x/day/orl man; Antitumor (Breast) PS131:95 ; Antitumor (Cervix) PJB1(2):287 ; Antitumor (Lung) PJB1(2):287 ; Antiviral PS75:161 ; Artemicide LC50=110 ppm PC29(5):1667 ; Cancer-Preventive 525 ; Candidicide QJC28:155 ; Estrogenic DUKE1992B ; Gonadotrophic JE28:221 ; Hepatoprotective PMP23:60 ; Hypocholesterolemic 2-6 g/man/day/orl M30 9-3,330 mg/man/day/orl MAR ; Hypoglycemic JE27:243 ; Hypolipidemic 2-6 g/day; Pesticide DUKE1992B ; Spermicide JE28:221 ; Ubiquiot JBH ; Ulcerogenic 500 mg/kg ipr rat FT63(1):3

CAFFEINE Leaf: DUKE1992A
Adenosine-Antagonist TEA ; Analeptic 200 scu mus BBE ; Analgesic-Synergist PJB1(2):263 ; Antiapneic M29 ; Antiapoptotic BOI ; Antiasthmatic 5-10 mg/kg orl/man M29 ; Anticarcinogenic PCF:305 ; Anticariogenic JD23:101 ; Antidermatitic M29 ; Antiemetic 411 ; Antifeedant 382 ; Antiflu EMP5:198 ; Antiherpetic EMP5:201 ; Antihypotensive 250 mg/day/orl/man M29 ; Antinarcotic 411 ; Antiobesity PCF:305 ; Antioxidant PC27:974 ; Antirhinitic 140 mg/day/orl/man M29 ; Antiserotonergic 40 ipr rat BBE 40 scu rat BBE ; Antitumor PCF:305 ; Antitumor (Lung) NR54:S71 ; Antivaccinia EMP5:201 ; Antiviral V&D ; Apoptotic BOI ; cAMP-Phosphodiesterase-Inhibitor PAM ; Cancer-Preventive 525 ; Cardiotonic 10-25 orl dog BBE 65-500 orl cat BBE ; Catabolic ABS ; cGMP-Phosphodiesterase-Inhibitor PAM ; Choleretic DUKE1992B ; CNS-Stimulant 100 orl mus 30 orl rat; Coronary-Dilator TEA ; Diuretic; Energizer 20-200 mg/man JAM272:1043 ; Ergotamine-Enhancer M29 ; FLavor FEMA 125 ARC ; Herbicide 500 ; Hypertensive; Hypoglycemic EMP6:168 ; Insecticide 382 ; Myorelaxant TEA ; Neurotoxic RJH ; Pesticide DUKE1992B ; Phosphodiesterase-Inhibitor PJB1(2):263 ; Pyrogenic 13.3 mg/kg ipr rbt EJP45:389 15 mg/kg ipr cat EJP45:389 60 mg/day oral hmn ALG51:189 ; Respirastimulant; Stimulant RJH ; Teratogenic 14 orl rat BBE ; Topoisomerase-I-Inhibitor 0.1 nM JEM168:129 75 uM TCM10:41 ; Topoisomerase-II-Inhibitor 99 mM TCM10:41 ; Vasodilator DUKE1992B

FRIEDELIN-3ALPHA-ACETATE Plant: DUKE1992A
No activity reported.

FRIEDELIN-3BETA-OL Plant: DUKE1992A
No activity reported.

MUCILAGE Fruit: DUKE1992A
Cancer-Preventive 525 ; Demulcent PJB1(2):279

References

382: Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
411: Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
500: Jim Duke's personal files
525: Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
ABS: Abstract (See species file)
ALG51:189: Daroca, P., Rodriguez, J., Reano, M., Canto, G., Miranda, P. 1996. Fever From Caffeine. Allergy, 51(3): 189-191.
ARC: Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Note: Most ARC numerical data were in mg/dl. I know of no other plant where zinc is more prevalent than other minerals and protein. These data should be viewed as suspect.
BBE: Borchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
BOI: Jim Duke's personal files
DFN:160: Jim Duke's personal files
DUKE1992A: Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.
DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.
EJP45:389: Dascombe, M. J. 1977. Effects of Methylxanthine Drugs on Pyrogen-Induced Hyperthermia. Eur J Pharmacol, 45: 389-392.
EMP5:198: Economic & Medicinal Plant Research, 5: 198.
EMP5:201: Jim Duke's personal files
EMP5:363: Economic & Medicinal Plant Research, 5: 363.
EMP6:168: Jim Duke's personal files
FT63(1):3: Jim Duke's personal files
FT68(4):291: Jim Duke's personal files
JAFC37:1365: Jim Duke's personal files
JAM272:1043: Jim Duke's personal files
JBH: Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
JD23:101: Jim Duke's personal files
JE27:243: Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
JE28:221: Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
JEM168:129: Tohda, H., Zhao, J. H., Oikawa, A. 1992. A Possible Involvement of DNA Topoisomerase I in "Caffeine Effect" After Ultraviolet Irradiation. Tohoku J Exp Med, 168: 129-132.
M11: Merck 11th Edition
M29: Martindale's 29th
M30: Martindale's 30th
MAR: Martindale's 28th
NR54:S71: Jim Duke's personal files
PAM: Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
PC27:974: Jim Duke's personal files
PC29(5):1667: Jung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
PCF:305: Jim Duke's personal files
PJB1(2):263: Jim Duke's personal files
PJB1(2):279: Jim Duke's personal files
PJB1(2):287: Jim Duke's personal files
PMP23:60: Jim Duke's personal files
PS131:95: Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
PS75:161: Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
QJC28:155: Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
RJH: R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
TCM10:41: Shin, C. G., Strayer, J. M., Wani, M., Snapka, R. M. 1990. Rapid Evaluation of Topoisomerase Inhibitors: Caffeine Inhibition of Topoisomerases in vivo. Teratogen Carcinogen Mutagen, 10: 41-52.
TEA: McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
V&D: Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.

ppm = parts per million
tr = trace

Phytochemical Database, USDA - ARS - NGRL, Beltsville Agricultural Research Center, Beltsville, Maryland
Thu May 16 17:08:16 EDT 2002

Please send questions and comments to:

James A. Duke (E-Mail: JimDuke@cpcug.org)
or
Stephen M. Beckstrom-Sternberg (E-Mail: SteveBS@nhgri.nih.gov)

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