Dr. Duke's
Phytochemical and Ethnobotanical Databases

Chemicals and their Biological Activities in: Jateorhiza palmata MIERS (Menispermaceae) -- Calumba Root

Chemicals

ALKALOIDS Root 20,000 - 43,000 ppm DUKE1992A

No activity reported.

BISJATRORRHIZINE Root: DUKE1992A

No activity reported.

CALUMBIN Root: DUKE1992A

No activity reported.

CHASMANTHIN Root: DUKE1992A

No activity reported.

COLUMBAMINE Root: DUKE1992A

Antibacterial DUKE1992B ; Antimalarial 0.72 ug/ml JE32:161 ; Choleretic DUKE1992B ; CNS-Depressant DUKE1992B ; Enterotonic DUKE1992B ; Hypotensive DUKE1992B ; Pesticide DUKE1992B

COLUMBIN Root: DUKE1992A

No activity reported.

COLUMBIN-2,3-EPOXIDE Root: DUKE1992A

No activity reported.

COLUMBINYL-GLUCOSIDE Plant: DUKE1992A

No activity reported.

CRYPTOGENIN Root: DUKE1992A

No activity reported.

DIOSGENIN Root: DUKE1992A

Antifatigue JE26:85 ; Antiinflammatory PH2 ; Antistress JE26:85 ; Estrogenic 20-40 mg/kg/day/15 day scu mus; Hepatoprotective PH2 ; Hypocholesterolemic PMP23:57 ; Mastogenic

EO Root 700 - 15,000 ppm DUKE1992A

No activity reported.

EX(METHANOL) Plant: DUKE1992A

No activity reported.

ISOJATEORINYL-GLUCOSIDE Plant: DUKE1992A

No activity reported.

JATEORINE Root: DUKE1992A

No activity reported.

JATEORINYL-GLUCOSIDE Plant: DUKE1992A

No activity reported.

JATEORRHIZINE Root: DUKE1992A

Antiinflammatory DUKE1992B ; CNS-Depressant DUKE1992B ; CNS-Stimulant DUKE1992B ; Enterotonic DUKE1992B ; Hypotensive DUKE1992B

MUCILAGE Root: DUKE1992A

Cancer-Preventive 525 ; Demulcent PJB1(2):279

PALMARIN Root: DUKE1992A

No activity reported.

PALMATINE Root 20,000 ppm; DUKE1992A

Abortifacient DUKE1992B ; Adrenocorticotrophic DUKE1992B ; Analgesic DUKE1992B ; Antialzheimeran? 411 ; Antiarrhythmic DUKE1992B ; Antibacterial DUKE1992B ; Anticholinesterase 411 ; Antiinfarctal PMP25:57 ; Antiinflammatory DUKE1992B ; Antimalarial PR4(4):131 ; Antipyretic GMJ ; CNS-Depressant DUKE1992B ; Hypotensive 411 ; Inotropic DUKE1992B ; Pesticide DUKE1992B ; Respiradepressant DUKE1992B ; Uterotonic 411

STARCH Root 300,000 - 350,000 ppm DUKE1992A

Absorbent M29 ; Antidote (Iodine) JBH ; Antinesidioblastosic M29 ; Emollient M29 ; Poultice M29

TANNIN Root: DUKE1992A

Anthelminthic JNP59:205 ; Antibacterial JE26:74 ; Anticancer JAF47:397 ; Anticariogenic JNP59:205 ; Antidiarrheic DUKE1992B ; Antidysenteric DUKE1992B ; Antihepatotoxic JNP59:205 ; AntiHIV JNP59:205 ; Antihypertensive JNP59:205 ; Antilipolytic JNP59:205 ; Antimutagenic DUKE1992B ; Antinephritic CPB38:1049 ; Antiophidic EMP5:363 ; Antioxidant 1/3 quercetin JAF47:397 IC50=1.44 ug/ml CPB38:1051 ; Antiradicular 1/3 quercetin JAF47:397 500 mg/kg/day orl mus CPB38:1049 ; Antirenitic CPB38:1049 ; Antitumor; Antitumor-Promoter JAF47:397 ; Antiulcer JNP59:205 ; Antiviral; Cancer-Preventive HG22:14 ; Carcinogenic AHP156 ; Chelator JNP59:205 ; Cyclooxygenase-Inhibitor JNP59:205 ; Glucosyl-Transferase-Inhibitor JNP59:205 ; Hepatoprotective DUKE1992B ; Immunosuppressant RWG29 ; Lipoxygenase-Inhibitor JNP59:205 ; MAO-Inhibitor JNP59:205 ; Ornithine-Decarboxylase-Inhibitor JNP59:205 ; Pesticide DUKE1992B ; Psychotropic CPB38:1049 ; Xanthine-Oxidase-Inhibitor JNP59:205

THYMOL Essential Oil: DUKE1992A

Allergenic M&R366 ; Analgesic MAD ; Ancylostomicide MAD ; Anesthetic MAD ; Anthelminthic 411 ; Antiacne NIG ; Antiaggregant IC50=0.75 TRA42:511 ; Antialzheimeran? LGR ; Antiarthritic MAD ; Antiatherosclerotic IC50=4 uM JAF45:578 ; Antibacterial MIC=50-400 ug/ml; Antibronchitic MAD ; Anticariogenic MIC=200-400 ug/ml JNP59:823 ; Anticholinesterase LGR ; Antihalitosic AH12(4):17 ; Antiherpetic MAR ; Antiinflammatory (=indomethacin) DFN:161 ; Antilepric MAD ; Antimelanomic IC50=120 uM/l JN127:668 ; Antineuritic DUKE1992B ; Antioxidant 100 ppm MAR ; Antioxidant (LDL) IC50=4 uM JAF45:578 ; Antiperiodontic MIC=50-200 ug/ml JNP59:823 ; Antiplaque MIC=39-625 ug/ml 451 ; Antiradicular EC=60 JEO5:153 ; Antirheumatic 411 ; Antiseptic 20 x phenol W&W ; Antispasmodic; Antistaphylococcic JAR10:7 ; Antistreptococcic MIC=200-400 ug/ml JNP59:823 ; Antitrichinosic 5% MAD ; Antitussive IWU ; Ataxigenic ZEB ; Candidicide 100 ug/ml (>Nystatin) JE58:143 ; Carminative JPP46:16 ; Counterirritant NIG ; Cyclooxygenase-Inhibitor (=indomethacin) DFN:161 ; Dentifrice ARC ; Deodorant MAR ; Dermatitigenic M&R366 ; Enterorelaxant JAR4:22 ; Enterotoxic WIC ; Expectorant LAF ; FLavor FEMA 2-100 ARC ; Fungicide M11 ; Gastroirritant M29 ; Gram(+)icide MIC=200-400 ug/ml JNP59:823 ; Gram(-)icide MIC=50-200 ug/ml JNP59:823 ; Irritant LAF ; Larvicide 10 ppm 454 ; Molluscicide PR13:649 ; Myorelaxant JAR4:22 ; Nematicide MLC=0.1 mg/ml SZ44:183 ; Perfumery ARC ; Pesticide DUKE1992B ; Sedative ZEB ; Sprout-Inhibitor PER.COM.SFV ; Tracheorelaxant DUKE1992B ; Trichomonicide LD100=25 ug/ml FT67:279 ; Urinary-Antiseptic 411 ; Vermicide MAD

References

411: Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.

451: Osawa, K., Matsumoto, T., Maruyama, T., Takiguchi, T., Okuda, K., and Takazoe, I., Studies of the antibacterial activity of plant extracts and their constituents against periodontopathic bacteria, Bull Tokyo Dent. Coll., 31 (1), 1990, 17-21

454: Berenbaum, M. R., The natives knew, Chemtech, (May), 1990, 275-279.

525: Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.

AH12(4):17: American Health, 12(4): 17, 1993.

AHP156: Jim Duke's personal files

ARC: Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry Note: Most ARC numerical data were in mg/dl. I know of no other plant where zinc is more prevalent than other minerals and protein. These data should be viewed as suspect.

CPB38:1049: Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.

CPB38:1051: Jim Duke's personal files

DFN:161: Jim Duke's personal files

DUKE1992A: Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.

DUKE1992B: Duke, James A. 1992. Handbook of biologically active phytochemicals and their activities. Boca Raton, FL. CRC Press.

EMP5:363: Economic & Medicinal Plant Research, 5: 363.

FT67:279: Jim Duke's personal files

GMJ: Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.

HG22:14: HerbalGram No. 22 - Spring 1990, page 14.

IWU: Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.

JAF45:578: Jim Duke's personal files

JAF47:397: Jim Duke's personal files

JAR10:7: Jim Duke's personal files

JAR4:22: J. Aromatherapy 4: 22.

JBH: Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.

JE26:74: Jim Duke's personal files

JE26:85: Jim Duke's personal files

JE32:161: Jim Duke's personal files

JE58:143: Jim Duke's personal files

JEO5:153: Jimenez, J., Navarro, M.C., Montilla, M.P., Martin, A. and Martinez, A. 1993. Thymus zygis Oil: Its Effects on CCl4-Induced Hepatotoxicity and Free Radical Scavenger Activity. JEO5: 153-8.

JN127:668: Jim Duke's personal files

JNP59:205: Jim Duke's personal files

JNP59:823: Jim Duke's personal files

JPP46:16: Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.

LAF: Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.

LGR: L. Gracza (1985) as cited by Buchbauer re antiacetylcholinesterase.

M&R366: Jim Duke's personal files

M11: Merck 11th Edition

M29: Martindale's 29th

MAD: Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.

MAR: Martindale's 28th

NIG: Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.

PER.COM.SFV: Duke, J.A.. Personal Communication.

PH2: Jim Duke's personal files

PJB1(2):279: Jim Duke's personal files

PMP23:57: Jim Duke's personal files

PMP25:57: Jim Duke's personal files

PR13:649: Jim Duke's personal files

PR4(4):131: Jim Duke's personal files

RWG29: Jim Duke's personal files

SZ44:183: Shoyakugaku Zasshi, 44: 183.

TRA42:511: Tramil, 42: 511.

W&W: Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)

WIC: Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.

ZEB: Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.

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